[Compounds similar to acyclovir. VI. Synthesis of optically active 1',2'-seconucleosides].

Abstract

A convenient method is suggested of synthesis of (3R, 4R)-, (3S, 4S)- and (3R/S, 4S/R)-dihydroxy-3-hydroxymethyl-2-oxapentyl derivatives of the, cytosine, uracyl, adenine and guanine ("full" acyclic analogues of nucleosides with C1'-C2' bond cleaved) by condensation of trimethylsilyl derivatives of nucleic bases (sodium salt in case of adenine) with (3$, 4R… (More)

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@article{Smirnov1990CompoundsST, title={[Compounds similar to acyclovir. VI. Synthesis of optically active 1',2'-seconucleosides].}, author={Igor P. Smirnov and Svetlana V. Kochetkova and T L Tsilevich and Alexander A Khorlin and B. P. Gottikh and V. L. Florent'ev}, journal={Bioorganicheskaia khimiia}, year={1990}, volume={16 10}, pages={1355-61} }