Compositional heterogeneity of the Escherichia coli genome: A role for VSP repair?

  title={Compositional heterogeneity of the Escherichia coli genome: A role for VSP repair?},
  author={Gabriel Guti{\'e}rrez and Josep M Casades{\'u}s and Jos{\'e} L. Oliver and Antonio Marine},
  journal={Journal of Molecular Evolution},
E. coli genes that contain a high frequency of the tetranucleotide CTAG are also rich in the tetramers CTTG, CCTA, CCAA, TTGG, TAGG, and CAAG (group-I tetramers). Conversely, E. coli genes lacking CTAG are rich in the tetranucleotides CCTG, CCAG, CTGG, and CAGG (group-II tetramers). These two gene samples differ also in codon usage, amino acid composition, frequency of Dcm sites, and contrast vocabularies. Group-I tetramers have in common that they are depleted by very-short-patch repair (VSP… CONTINUE READING


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