Compositional gradients in Gramineae genes.

@article{Wong2002CompositionalGI,
  title={Compositional gradients in Gramineae genes.},
  author={Gane Ka-Shu Wong and Jun Wang and Lin Tao and Jun Tan and Jianguo Zhang and Douglas A. Passey and Jun Yu},
  journal={Genome research},
  year={2002},
  volume={12 6},
  pages={851-6}
}
In this study, we describe a property of Gramineae genes, and perhaps all monocot genes, that is not observed in eudicot genes. Along the direction of transcription, beginning at the junction of the 5'-UTR and the coding region, there are gradients in GC content, codon usage, and amino-acid usage. The magnitudes of these gradients are large enough to hinder the annotation of the rice genome and to confound the detection of protein homologies across the monocot-eudicot divide. 

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