Compositional and immunobiological analyses of extracellular vesicles released by Candida albicans.

  title={Compositional and immunobiological analyses of extracellular vesicles released by Candida albicans.},
  author={Gabriele Vargas and Juliana Dutra B. Rocha and Debora Leite Oliveira and Priscila Costa Albuquerque and Susana Fras{\'e}s and Suelen S. Santos and Joshua D Nosanchuk and Andre M O Gomes and Lia Carolina Soares Medeiros and Kildare Miranda and Tiago Jose Paschoal Sobreira and Ernesto S. Nakayasu and Emma A Arigi and Arturo Casadevall and Allan J Guimaraes and Marcio Lourenço Rodrigues and C{\'e}lio Geraldo Freire-de-Lima and Igor C. Almeida and Leonardo Nimrichter},
  journal={Cellular microbiology},
  volume={17 3},
The release of extracellular vesicles (EV) by fungal organisms is considered an alternative transport mechanism to trans-cell wall passage of macromolecules. Previous studies have revealed the presence of EV in culture supernatants from fungal pathogens, such as Cryptococcus neoformans, Histoplasma capsulatum, Paracoccidioides brasiliensis, Sporothrix schenckii, Malassezia sympodialis and Candida albicans. Here we investigated the size, composition, kinetics of internalization by bone marrow… CONTINUE READING
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