Composition of the early intestinal microbiota: knowledge, knowledge gaps and the use of high-throughput sequencing to address these gaps.

@article{Fouhy2012CompositionOT,
  title={Composition of the early intestinal microbiota: knowledge, knowledge gaps and the use of high-throughput sequencing to address these gaps.},
  author={Fiona Fouhy and R Paul Ross and Gerald F. Fitzgerald and Catherine Stanton and Paul D Cotter},
  journal={Gut microbes},
  year={2012},
  volume={3 3},
  pages={203-20}
}
The colonization, development and maturation of the newborn gastrointestinal tract that begins immediately at birth and continues for two years, is modulated by numerous factors including mode of delivery, feeding regime, maternal diet/weight, probiotic and prebiotic use and antibiotic exposure pre-, peri- and post-natally. While in the past, culture-based approaches were used to assess the impact of these factors on the gut microbiota, these have now largely been replaced by culture… CONTINUE READING