Composition of the Synaptic PSD-95 Complex*□S

Abstract

Postsynaptic density protein 95 (PSD-95), a specialized scaffold protein with multiple protein interaction domains, forms the backbone of an extensive postsynaptic protein complex that organizes receptors and signal transduction molecules at the synaptic contact zone. Large, detergentinsoluble PSD-95-based postsynaptic complexes can be affinity-purified… (More)

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