Composition of fatty oils from Semen Ziziphi Spinosae and its cardiotonic effect on isolated toad hearts

  title={Composition of fatty oils from Semen Ziziphi Spinosae and its cardiotonic effect on isolated toad hearts},
  author={Junbo Xie and Yanqing Zhang and Lijuan Wang and Wuqin Qi and Mingchun Zhang},
  journal={Natural Product Research},
  pages={479 - 483}
In this study, the composition of fatty oil from Semen Ziziphi Spinosae and its cardiotonic activity on the heart isolated from a toad were studied. Oil-in-water (O/W) emulsions of fatty oil were prepared by the perfusion method. The fatty oil had a positive inotropic effect on isolated rat hearts at a concentration between 5 × 10−3 and 2 × 10−2 mL/10 mL, and the effect was in positive correlation with the concentration of calcium ions. In addition, this effect was inhibited by 2 mg/mL… 

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