Composition of Gomori-positive inclusions in astrocytes of the hypothalamic arcuate nucleus.

@article{Brawer1994CompositionOG,
  title={Composition of Gomori-positive inclusions in astrocytes of the hypothalamic arcuate nucleus.},
  author={James Brawer and Roland Stein and Lorne Small and Soriba Ciss{\'e} and Hyman M. Schipper},
  journal={The Anatomical record},
  year={1994},
  volume={240 3},
  pages={
          407-15
        }
}
BACKGROUND Astrocytes within the hypothalamic arcuate nucleus contain Gomori-positive inclusions that exhibit a nonenzymatic peroxidase activity. The source and composition of these Gomori-positive inclusions are currently unknown. Recent evidence, derived from cultured astrocytes, suggests that Gomori-positive inclusions may consist of autophagocytized accumulations of altered mitochondria and that the peroxidase activity is generated by iron or other metals which accumulate in these… CONTINUE READING