Composition of Gomori‐positive inclusions in astrocytes of the hypothalamic arcuate nucleus

@article{Brawer1994CompositionOG,
  title={Composition of Gomori‐positive inclusions in astrocytes of the hypothalamic arcuate nucleus},
  author={J. Brawer and R. Stein and L. Small and S. Ciss{\'e} and H. Schipper},
  journal={The Anatomical Record},
  year={1994},
  volume={240}
}
  • J. Brawer, R. Stein, +2 authors H. Schipper
  • Published 1994
  • Biology, Medicine
  • The Anatomical Record
  • Background: Astrocytes within the hypothalamic arcuate nucleus contain Gomori‐positive inclusions that exhibit a nonenzymatic peroxidase activity. The source and composition of these Gomori‐positive inclusions are currently unknown. Recent evidence, derived from cultured astrocytes, suggests that Gomori‐positive inclusions may consist of autophagocytized accumulations of altered mitochondria and that the peroxidase activity is generated by iron or other metals which accumulate in these… CONTINUE READING
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