Composition, variability, and temporal stability of the intestinal microbiota of the elderly.

@article{Claesson2011CompositionVA,
  title={Composition, variability, and temporal stability of the intestinal microbiota of the elderly.},
  author={Marcus J. Claesson and Siobh{\'a}n Cusack and Orla O'Sullivan and Rachel Greene-Diniz and Heleen H de Weerd and Edel Flannery and Julian R Marchesi and Daniel Falush and Timothy G Dinan and Gerald Fitzgerald and Catherine Stanton and D van Sinderen and Michael H. O'Connor and Norma Harnedy and KIERAN M. O'CONNOR and Colm Henry and Denis O'Mahony and Anthony P. Fitzgerald and F Shanahan and Cillian Twomey and C. Ray Hill and R Paul Ross and Paul W O'Toole},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2011},
  volume={108 Suppl 1},
  pages={4586-91}
}
Alterations in the human intestinal microbiota are linked to conditions including inflammatory bowel disease, irritable bowel syndrome, and obesity. The microbiota also undergoes substantial changes at the extremes of life, in infants and older people, the ramifications of which are still being explored. We applied pyrosequencing of over 40,000 16S rRNA gene V4 region amplicons per subject to characterize the fecal microbiota in 161 subjects aged 65 y and older and 9 younger control subjects… CONTINUE READING
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