Composition, morphology and mechanics of hagfish slime

@article{Fudge2005CompositionMA,
  title={Composition, morphology and mechanics of hagfish slime},
  author={Douglas S. Fudge and Nimrod Levy and Scott Chiu and John M. Gosline},
  journal={Journal of Experimental Biology},
  year={2005},
  volume={208},
  pages={4613 - 4625}
}
SUMMARY Hagfish slime consists of mucins and protein threads that are released from slime glands and mix with seawater to produce an ephemeral material with intriguing physical properties. We recently characterized the mechanics of the slime's fibrous component, and here we report the first mechanical properties of the mucin component and the slime as a whole. Our results suggest that hagfishes can produce remarkable quantities of the slime because it is almost three orders of magnitude more… Expand
Physiology, biomechanics, and biomimetics of hagfish slime.
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TLDR
Hagfish slime, thickening in elongation and thinning in shear, presents a sophisticated natural high water content gel with flow properties that may be beneficial for both, defense and escape. Expand
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TLDR
Evidence is provided that mixing and mucin vesicles are indeed crucial for skein unraveling and that the deployment of thread skeins via their interaction with shear-elongated mucins represents a unique mechanism in biology and may lead to novel technologies for transmitting hydrodynamic forces to microscale particles that would typically be immune to such forces. Expand
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Structure and dynamics of hagfish mucin in different saline environments.
TLDR
Shear rheology revealed that hagfish mucin possesses pronounced viscoelastic properties at high concentrations at 3 mg ml-1, showing that mucin alone achieves mechanical properties similar to those of natural hag fish slime (mucins and protein threads). Expand
Stabilization and swelling of hagfish slime mucin vesicles
TLDR
In vitro rupture assays demonstrated that both TMAO and betaine had a significant effect on rupture, but neither was capable of completely abolishing mucin swelling and rupture, even at high concentrations, which suggests that some other mechanism such as the chemical microenvironment within gland mucous cells, or hydrostatic pressure is responsible for stabilization of the vesicles within the gland. Expand
Spontaneous unraveling of hagfish slime thread skeins is mediated by a seawater-soluble protein adhesive
TLDR
This study provides a mechanism for the deployment of thread skeins in Pacific hagfish slime, and raises the possibility of producing novel biomimetic protein adhesives that are salt, temperature and kosmotrope sensitive. Expand
A revised model of hagfish slime mucous vesicle stabilization and deployment.
TLDR
The hypothesis that vesicles contain polyanionic glycoproteins stabilized by divalent cations and deploy in seawater via exchange of divalent for monovalent cations is tested and it is found that the hagfish slime mucous gel is in fact polycationic in nature. Expand
Hagfish slime exudate stabilization and its effect on slime formation and functionality
TLDR
Loss of functionality of hagfish slime exudate during storage is driven by mucin vesicle rupture when stabilized in oil and by gradually inhibited skein unraveling when stabilize in buffer, suggesting that a water soluble protein glue denatures and gradually becomes insoluble during storage in CP buffer. Expand
THE SKIN | Hagfish Slime
TLDR
Hagfish slime is the ultra-dilute material that is formed when hagfishes eject the contents of their slime glands into seawater, believed to function as a defense against gill-breathing predators. Expand
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TLDR
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TLDR
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TLDR
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