Composite tissue allotransplantation: hand transplantation and beyond.

@article{Shores2010CompositeTA,
  title={Composite tissue allotransplantation: hand transplantation and beyond.},
  author={Jaimie T. Shores and Gerald Brandacher and Stefan Schneeberger and Vijay S. Gorantla and W. P. Andrew Lee},
  journal={The Journal of the American Academy of Orthopaedic Surgeons},
  year={2010},
  volume={18 3},
  pages={
          127-31
        }
}
Recent advances in transplant immunology are shifting the focus from immunosuppression to immunoregulation, making composite tissue allotransplantation with novel and less potent immunosuppressive regimens a possibility. Hand transplantation has been the most frequently performed human composite tissue allotransplantation, with more than 50 upper extremity-based transplants done worldwide. Further research is needed regarding immunomodulating protocols, and careful oversight and individualized… CONTINUE READING

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