Composite polymeric magnetic nanoparticles for co-delivery of hydrophobic and hydrophilic anticancer drugs and MRI imaging for cancer therapy.

@article{Singh2011CompositePM,
  title={Composite polymeric magnetic nanoparticles for co-delivery of hydrophobic and hydrophilic anticancer drugs and MRI imaging for cancer therapy.},
  author={Abhalaxmi Singh and Fahima Dilnawaz and Sujeet Mewar and Uma R Sharma and Narnamangalam R Jagannathan and Sanjeeb Kumar Sahoo},
  journal={ACS applied materials & interfaces},
  year={2011},
  volume={3 3},
  pages={842-56}
}
Exercising complementary roles of polymer-coated magnetic nanoparticles for precise drug delivery and image contrast agents has attracted significant attention in biomedical applications. The objective of this study was to prepare and characterize magnetic nanoparticles embedded in polylactide-co-glycolide matrixes (PLGA-MNPs) as a dual drug delivery and imaging system capable of encapsulating both hydrophilic and hydrophobic drugs. PLGA-MNPs were capable of encapsulating both hydrophobic and… CONTINUE READING
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