Seven soft red winter wheat cultivars were evaluated for partial resistance to Leptosphaeria nodorum under field conditions. The results demonstrate that resistance is available among cultivars that are adapted to the southeastern U.S. and that resistance is long lasting. Resistant cultivars had longer incubation and latent periods, slower rates of lesion development, and reduced the level of sporulation of L. nodorum. Seedlings of susceptible cultivars sustained severe disease with dew periods as short as 48 hr in greenhouse tests. One resistant cultivar sustained little damage with dew period as long as 144 hr. Latent period was shortest on the second leaf below the flag leaf (F-2 leaf) of all cultivars and longest on the flag leaf which reflected the effect of microclimate and leaf age. The range in length of latent period on the flag, F-1, and F-2 leaves of resistant cultivars was less than that for susceptible cultivars. Differences between cultivars were greatest (up to 6.8 days) for the F-2 leaf. A delay in production of inoculum on the F-2 and lower leaves of resistant cultivars should delay infection of the flag leaf and spike. The greatest differentiation among cultivars for sporulation of L. nodorum was on upper leaves at Feekes growth stage 11.2. ‘Oasis’ consistently had less sporulation than other cultivars at all sampling dates and leaf positions. The rate of disease progress up the plant (disease severity) and area under the disease progress curve were also least on ‘Oasis’. There were significant correlations among components of resistance and associated components suggesting that a single or interrelated mechanisms control expression of resistance. Overall, ‘Oasis’ was the most resistant cultivar followed by ‘Coker 762’ and ‘Coker 747’. There cultivars have remained resistant for ten or more years. ‘Stacy’ was intermediate in resistance and was the most variable of the seven cultivars for the components tested. ‘Holley’, ‘Omega 78’, and ‘Florida 301’ were highly susceptible by all criteria tested. Plant height was not a factor in resistance. The resistant cultivars are mostly later in maturity than the susceptible cultivars. In this study, crop maturity was similar under existing environmental conditions during the two seasons when most data were collected.