Components of lemon essential oil attenuate dementia induced by scopolamine

@article{Zhou2009ComponentsOL,
  title={Components of lemon essential oil attenuate dementia induced by scopolamine},
  author={Wenjun Zhou and Syuichi Fukumoto and Hidehiko Yokogoshi},
  journal={Nutritional Neuroscience},
  year={2009},
  volume={12},
  pages={57 - 64}
}
Abstract The anti-dementia effects of s-limonene and s-perillyl alcohol were observed using the passive avoidance test (PA) and the open field habituation test (OFH). These lemon essential oils showed strong ability to improve memory impaired by scopolamine; however, s-perillyl alcohol relieved the deficit of associative memory in PA only, and did not improve non-associative memory significantly in OFH. Analysis of neurotransmitter concentration in some brain regions on the test day showed that… Expand
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References

SHOWING 1-10 OF 40 REFERENCES
Effect of flavour components in lemon essential oil on physical or psychological stress
Citrus essential oils, including lemon essential oil, have long been used widely in aromatherapy and alternative medicine. This study was designed to assess the effects of flavour components in lemonExpand
Effect of bicuculline and angiotensin II fragment 3-7 on learning and memory processes in rats chronically treated with ethanol.
TLDR
Bicuculline significantly improved acquisition in the active avoidance test in the control and alcohol-intoxicated groups of rats, and when the drug was given together with AII 3-7 significantly enhanced its action in the Control group and in rats chronically treated with ethanol. Expand
Effects of long-term exposure of lemon essential oil odor on behavioral, hormonal and neuronal parameters in male and female rats
TLDR
Long-term exposure to lemon EO can induce significant, at times sex-specific, changes in neuronal circuits involved in anxiety and pain, and Corticosterone was lower in EO-exposed animals of both sexes than in their controls. Expand
Intraseptal injection of scopolamine increases the effect of systemic diazepam on passive avoidance learning and emotionality in rats.
TLDR
The data are consistent with the hypothesis that peripheral administration of behaviorally effective doses of diazepam on passive avoidance learning might act partially via a septal ACh-GABA/benzodiazepine mechanism. Expand
Concurrent muscarinic and β-adrenergic blockade in rats impairs place-learning in a water maze and retention of inhibitory avoidance
TLDR
These experiments examined the effects of separate and concurrent muscarinic cholinergic and beta-adrenergic blockade on inhibitory (passive) avoidance performance and spatial learning in the Morris water maze to support a role for interactions between norepinephrine and acetylcholine in the modulation of learning and memory. Expand
Cholinergic and dopaminergic agents which inhibit a passive avoidance response attenuate the paradigm-specific increases in NCAM sialylation state
  • E. Doyle, C. Regan
  • Psychology, Medicine
  • Journal of Neural Transmission / General Section JNT
  • 2005
TLDR
Observations provide further evidence of a regulatory role for neural cell adhesion molecule sialylation state in information storage processes in hippocampal immunoprecipitates. Expand
Effects of NMDA receptor antagonists on passive avoidance learning and retrieval in rats and mice
TLDR
The results indicate that in the passive avoidance task activation of NMDA receptors is involved in memory formation, but is not critical for the maintenance of memory or its retrieval. Expand
Effects of concomitant nicotinic and muscarinic blockade on spatial memory disturbance in rats are purely additive: Evidence from the morris water task
TLDR
The hypothesis of a reciprocal modulation between the two ACh receptors, raised by some authors, cannot be supported for spatial learning mechanisms, at least with regard to the Morris water maze paradigm. Expand
In‐vitro Inhibition of Human Erythrocyte Acetylcholinesterase by Salvia lavandulaefolia Essential Oil and Constituent Terpenes
TLDR
Sage (Salvia spp) essential oil and some of its constituent terpenes on human erythrocyte acetylcholinesterase were examined in‐vitro to study the effects of Salvia lavandulaefolia Vahl on memory. Expand
Flavor components of monoterpenes in citrus essential oils enhance the release of monoamines from rat brain slices
TLDR
It is suggested that the metabolites of these monoterpene compounds contained in citrus essential oils have a stronger effect on monoamine release from brain tissue than the monoterPene compounds themselves. Expand
...
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4
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