Components of Panax notoginseng saponins enhance the cytotoxicity of cisplatin via their effects on gap junctions.

@article{Zhang2013ComponentsOP,
  title={Components of Panax notoginseng saponins enhance the cytotoxicity of cisplatin via their effects on gap junctions.},
  author={Cui-ling Zhang and X. Tong and Benquan Qi and X. Yu and Shu-ying Dong and Suzhi Zhang and Xiaoming Li and Meiling Yu},
  journal={Molecular medicine reports},
  year={2013},
  volume={8 3},
  pages={
          897-902
        }
}
Previously, Panax notoginseng saponin (PNS)-induced enhancement of gap junction (GJ) formation or function was observed to be responsible for the increased cytotoxic action of cisplatin. PNS has three constituents, ginsenoside Rg1 and Rb1, and notoginsenoside R1. The active compounds in PNS responsible for enhancing the cytotoxicity of cisplatin remain unknown. Thus, the effects of the main components of PNS on the cytotoxicity of cisplatin were investigated, as well as the correlation with the… Expand
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DDDT_A_240511 551..565
Hai Liu 1,2 Jianqiong Yang 3 Wanqing Yang Shaonan Hu 1 Yali Wu 1 Bo Zhao 1 Haiyan Hu 1 Shouying Du 1 1School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, People’sExpand
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