Components derived from Pelargonium stimulate macrophage killing of Mycobacterium species.

@article{Kim2009ComponentsDF,
  title={Components derived from Pelargonium stimulate macrophage killing of Mycobacterium species.},
  author={Caroline E Kim and William J Griffiths and Peter W. Taylor},
  journal={Journal of applied microbiology},
  year={2009},
  volume={106 4},
  pages={1184-93}
}
AIMS To determine the capacity of extracts of Pelargonium reniforme and Pelargonium sidoides, plants of the Geraniaceae family, to stimulate the uptake and killing of mycobacteria by murine macrophages and to identify the constituents that are responsible. METHODS AND RESULTS Bioassay-guided fractionation of aqueous P. reniforme extracts yielded five chemically distinct structures with the capacity to increase the rate of intracellular killing by macrophages. These were: gallic acid, methyl… CONTINUE READING