Component Composition of Gentamicin Sulfate Preparations
@article{Vydrin2004ComponentCO, title={Component Composition of Gentamicin Sulfate Preparations}, author={A. Vydrin and I. V. Shikhaleev and V. L. Makhortov and N. N. Shcherenko and N. V. Kolchanova}, journal={Pharmaceutical Chemistry Journal}, year={2004}, volume={37}, pages={448-450} }
Gentamicin sulfate is a widely used drug obtained by isolation and purification of a gentamicin complex of aminoglycoside antibiotics produced by some microorganisms. The main components of this complex are group C gentamicins, in particular, gentamicins C 1 , C 1a , and C 2 . It was reported that the these components account for about 80% of the gentamicin complex and possess approximately equal activities as antibiotics with respect to microorganisms [1]. The remaining 20% are the so-called… CONTINUE READING
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References
SHOWING 1-2 OF 2 REFERENCES
Navashin, Antibiotics of the Aminoglycoside Group [in Russian], Meditsina
- Moscow
- 1977
Biological activity of the antibiotic components of the gentamicin complex.
- Biology, Medicine
- Journal of bacteriology
- 1967
- 50
- PDF