Complications of pregnancy and transplacental transmission of relapsing-fever borreliosis.

  title={Complications of pregnancy and transplacental transmission of relapsing-fever borreliosis.},
  author={Christer S. Larsson and Marie Andersson and Betty P Guo and Annika Nordstrand and Inga Hagerstrand and Sara E Carlsson and Sven Bergstrom},
  journal={The Journal of infectious diseases},
  volume={194 10},
Relapsing-fever borreliosis caused by Borrelia duttonii is a common cause of complications of pregnancy, miscarriage, and neonatal death in sub-Saharan Africa. We established a murine model of gestational relapsing fever infection for the study of the pathological development of these complications. We demonstrate that B. duttonii infection during pregnancy results in intrauterine growth retardation, as well as placental damage and inflammation, impaired fetal circulation, and decreased… CONTINUE READING
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