Complications of povidone-iodine absorption in topically treated burn patients.

@article{Pietsch1976ComplicationsOP,
  title={Complications of povidone-iodine absorption in topically treated burn patients.},
  author={John B. Pietsch and Jonathan L. Meakins},
  journal={Lancet},
  year={1976},
  volume={1 7954},
  pages={280-2}
}
One of the dangers of topical therapy in thermal injuries is absorption of the therapeutic agent with subsequent metabolic and toxic complications. Two patients, one 30 years old with a 75% burn, the second 72 years old with a 35% burn, were treated topically with povidone-iodine ("Betadine", pH 2.43). In both patients severe metabolic acidosis developed which could not be attributed to sepsis, hypovolaemia, renal failure, diabetes, lactic acidaemia, &c. The acidosis associated with the 75… CONTINUE READING

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