Complications of Peptic Ulcer Disease

@article{Milosavljevic2011ComplicationsOP,
  title={Complications of Peptic Ulcer Disease},
  author={Tomica Milosavljevic and Mirjana Kosti{\'c}-Milosavljevi{\'c} and Ivan Jovanovi{\'c} and Miodrag Krstic},
  journal={Digestive Diseases},
  year={2011},
  volume={29},
  pages={491 - 493}
}
There are four major complications of peptic ulcer disease (PUD): bleeding, perforation, penetration, and obstruction. Complications can occur in patients with peptic ulcer of any etiology. Despite improvements in the medical management and the lower overall incidence of PUD, there are conflicting data about the incidence of potentially life-threatening ulcer complications. There are important time trends embedded within this stable overall rate of complications: the dramatic decline in the… 
View on PubMed
doi.org
86 Citations
Highly Influential Citations
4
Background Citations
36

Figures from this paper

86 Citations

Complications of Peptic Ulcer Perforation: A Clinical Case Study
TLDR
It is noted that post operative pulmonary complications and wound infection are more in the alcoholics and smokers, and the incidence of perforation is more in middle aged males.
Peptic ulcer complications requiring surgery: what has changed in the last 50 years in Turkey.
TLDR
The aim of this study is to determine the time trends in complicated peptic ulcer disease and to state the effects of H2 receptor blockers, proton pump inhibitors (PPI), and H. pylori eradication therapies on these complications.
CASE REPORT- RECURRENT DUODENAL ULCER PERFORATION
TLDR
A case of a 70 year old man, who presented with recurrent episodes of duodenal perforation in an interval of 2 years is discussed, which is a surgeon's dilemma and has to be managed to each presentation.
Prognostic factors in peptic ulcer perforations: a retrospective 14-year study.
TLDR
Age, ASA score, and having comorbid disease were found to have an effect on both mortality and morbidity, and the duration of symptoms had no effect on mortality nor morbidity in the present study.
[Nonsteroidal Anti-inflammatory Drug and Aspirin-induced Peptic Ulcer Disease].
  • Y. Shim, Nayoung Kim
  • Medicine
    The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi
  • 2016
TLDR
The aim of this review is to provide an evidence-based knowledge regarding the mechanism, complications of treatment, and prevention strategies for NSAID- or aspirin-related peptic ulcer disease in Korea.
Clinical Study of Peptic Ulcer Disease
TLDR
It has been found that Duodenal ulcers are more common than gastric ulcers, and the majorly observed site of the ulcer pain is the epigastrium.
Helicobacter Pylori Infections in Peptic Ulcer Perforations: A Retrospective Analysis in Two Referral Hospitals in Douala, Cameroon
TLDR
A hospital-based retrospective cross-sectional study conducted through the review of patients’ records admitted for peptic ulcer perforations in Laquintinie and Douala General Hospitals over a period of 5 years observed a high prevalence of H. pylori infection in patients with peptic Ulcers in Sub-Saharan Africa.
Predictive Factors of Surgery in Peptic Stenosis of the Bulb
TLDR
Only gastric atony and seniority of the disease over 9 years were independent risk factors of resistance to the Proton pump inhibitors in multivariate study.
Peptic ulcer disease
TLDR
The presentation, causes and management of peptic ulcer disease in general practice is looked at.
RISK FACTORS AND CLINICAL CHARACTERISTICS OF PEPTIC ULCER PERFORATION IN SECONDARY REFERRAL CENTER OF WEST BENGAL
TLDR
The study found that the major risk factors associated with peptic (stomach, duodenum) ulcer perforation were Male, NSAIDs, Smoking, Alcohol, Comorbidities, lower socioeconomic status, acute onset of pain etc.
...
...

References

SHOWING 1-10 OF 11 REFERENCES
Duration of Survival after Peptic Ulcer Perforation
TLDR
Long-term prognosis of peptic ulcer perforation is poor, and risk factors for late mortality are age, severe concomitant diseases, and postinterventional complications.
Peptic ulcer perforation before and after the introduction of H2-receptor blockers and proton pump inhibitors.
TLDR
The incidence of perforation among men decreased, but that among women was stable, thus changing the sex ratio towards a female preponderance at the end of the study period.
Perforated Peptic Ulcer Disease: A Review of History and Treatment
TLDR
Surgery for PPU is still a subject of debate despite more than an era of published expertise, indicating the need for establishing guidelines.
Recent trends in admissions and mortality due to peptic ulcer in England: increasing frequency of haemorrhage among older subjects
TLDR
Admission rates for gastric and duodenal ulcer haemorrhage and duODenal Ulcer perforation increased among older subjects, over a time when prescriptions for proton pump inhibitors, low dose aspirin, oral anticoagulants, and SSRI increased.
Risk of upper gastrointestinal bleeding associated with use of low-dose aspirin.
Risk of upper gastrointestinal bleeding associated with use of low-dose aspirin
TLDR
The findings from this observational study raise the possibility that prophylactic use of low-dose aspirin may convey an increased risk of gastrointestinal bleeding, which may offset some of its benefits.
The role of endoscopy in the management of patients with peptic ulcer disease.
Endoscopic therapy of benign pyloric stenosis and gastric outlet obstruction
Purpose of review To examine the short and long-term success rates of balloon dilation of pyloric stenosis. Recent findings Several large studies have demonstrated high rates of success for the…
Gastroduodenal Perforation: Maximal or Minimal Intervention?
  • F. Lui, K. A. Davis
  • Medicine
    Scandinavian journal of surgery : SJS : official organ for the Finnish Surgical Society and the Scandinavian Surgical Society
  • 2010
TLDR
Nonoperative management in otherwise healthy patients has yielded good results, but its use in those who are poor surgical candidates due to severe comorbidities has not been formally examined.
Long-term follow-up of patients with gastric outlet obstruction related to peptic ulcer disease treated with endoscopic balloon dilatation and drug therapy.
...
...