Complications of Peptic Ulcer Disease

  title={Complications of Peptic Ulcer Disease},
  author={Tomica Milosavljevic and Mirjana Kosti{\'c}-Milosavljevi{\'c} and Ivan Jovanovi{\'c} and Miodrag Krstic},
  journal={Digestive Diseases},
  pages={491 - 493}
There are four major complications of peptic ulcer disease (PUD): bleeding, perforation, penetration, and obstruction. Complications can occur in patients with peptic ulcer of any etiology. Despite improvements in the medical management and the lower overall incidence of PUD, there are conflicting data about the incidence of potentially life-threatening ulcer complications. There are important time trends embedded within this stable overall rate of complications: the dramatic decline in the… 

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