Complexity of terminal airspace geometry assessed by lung computed tomography in normal subjects and patients with chronic obstructive pulmonary disease.

@article{Mishima1999ComplexityOT,
  title={Complexity of terminal airspace geometry assessed by lung computed tomography in normal subjects and patients with chronic obstructive pulmonary disease.},
  author={M. Mishima and T. Hirai and H. Itoh and Y. Nakano and H. Sakai and S. Muro and K. Nishimura and Y. Oku and K. Chin and M. Ohi and T. Nakamura and J. Bates and A. M. Alencar and B. Suki},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1999},
  volume={96 16},
  pages={
          8829-34
        }
}
  • M. Mishima, T. Hirai, +11 authors B. Suki
  • Published 1999
  • Medicine
  • Proceedings of the National Academy of Sciences of the United States of America
  • Increases in the low attenuation areas (LAA) of chest x-ray computed tomography images in patients with chronic obstructive pulmonary disease (COPD) have been reported to reflect the development of pathological emphysema. We examined the statistical properties of LAA clusters in COPD patients and in healthy subjects. In COPD patients, the percentage of the lung field occupied by LAAs (LAA%) ranged from 2.6 to 67.6. In contrast, LAA% was always <30% in healthy subjects. The cumulative size… CONTINUE READING
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