Complexity of diabetic nephropathy pathogenesis and design of investigations

  • Majid Tavafi
  • Published 2013 in Journal of renal injury prevention

Abstract

Diabetic nephropathy (DN) pathogenesis is very complex and multifactorial. There are several mechanisms or pathways that hyperglycemia leads to renal injuries. Each pathway makes renal injuries via several mediators. Some mediators are common between the pathways such as reactive oxygen species (ROS) and TGF-β and there are many overlaps and interference… (More)
DOI: 10.12861/jrip.2013.20

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