Complexity of danger: the diverse nature of damage-associated molecular patterns.

@article{Schaefer2014ComplexityOD,
  title={Complexity of danger: the diverse nature of damage-associated molecular patterns.},
  author={Liliana Schaefer},
  journal={The Journal of biological chemistry},
  year={2014},
  volume={289 51},
  pages={
          35237-45
        }
}
In reply to internal or external danger stimuli, the body orchestrates an inflammatory response. The endogenous triggers of this process are the damage-associated molecular patterns (DAMPs). DAMPs represent a heterogeneous group of molecules that draw their origin either from inside the various compartments of the cell or from the extracellular space. Following interaction with pattern recognition receptors in cross-talk with various non-immune receptors, DAMPs determine the downstream… CONTINUE READING
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