Complexity of MRI white matter hyperintensity assessments in relation to cognition in aging and dementia from the Sunnybrook Dementia Study.

@article{Gao2011ComplexityOM,
  title={Complexity of MRI white matter hyperintensity assessments in relation to cognition in aging and dementia from the Sunnybrook Dementia Study.},
  author={Fu-qiang Gao and Richard H. Swartz and Philip Scheltens and Farrell S Leibovitch and Alex Kiss and Kie Honjo and Sandra E. Black},
  journal={Journal of Alzheimer's disease : JAD},
  year={2011},
  volume={26 Suppl 3},
  pages={379-88}
}
PURPOSE Quantification methods for white matter hyperintensities (WMH) on Magnetic Resonance Imaging are heterogeneous, deterring their application. This study compared three WMH rating scales, varying in complexity, and a volumetric method, to evaluate trade-offs between complexity and clinical utility in differentiating dementia subgroups and in correlating with cognition. METHODS WMH were rated using the Fazekas, Age-Related White Matter Changes (ARWMC) and Scheltens scales, and segmented… CONTINUE READING

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