Complexities of targeting innate immunity to treat infection.

  title={Complexities of targeting innate immunity to treat infection.},
  author={Kelly L. Brown and C{\'e}line Cosseau and Jennifer L. Gardy and Robert E. W. Hancock},
  journal={Trends in immunology},
  volume={28 6},
Innate immunity is an ancient form of host defence that is activated rapidly to enable, through a multiplicity of effector mechanisms, defence against a broad spectrum of microbial threats. From this perspective, innate immunity has desirable characteristics of a therapy against infections, and, as a consequence, the innate immune system has become a major target for the development of therapeutics to control inflammation and immune defences. Although advances in the field have come at a… CONTINUE READING


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