Complexation of DNA with ruthenium organometallic compounds: the high complexation ratio limit.

  title={Complexation of DNA with ruthenium organometallic compounds: the high complexation ratio limit.},
  author={St{\'e}phane Despax and Fuchao Jia and Michel Pfeffer and P H{\'e}braud},
  journal={Physical chemistry chemical physics : PCCP},
  volume={16 22},
Interactions between DNA and ruthenium organometallic compounds are studied by using visible light absorption and circular dichroism measurements. A titration technique allowing for the absolute determination of the advancement degree of the complexation, without any assumption about the number of complexation modes is developed. When DNA is in excess, complexation involves intercalation of one of the organometallic compound ligands between DNA base pairs. But, in the high complexation ratio… 
6 Citations

Recent Developments in the Interactions of Classic Intercalated Ruthenium Compounds: [Ru(bpy)2dppz]2+ and [Ru(phen)2dppz]2+ with a DNA Molecule

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Oligonucleotide Complexes in Bioorganometallic Chemistry



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