Complexation in the heparin-metal ion system

  title={Complexation in the heparin-metal ion system},
  author={Mariana A. Feofanova and Yu. V. Frantseva and S. V. Lapshin},
  journal={Russian Journal of Coordination Chemistry},
The reaction of high-molecular weight heparin with Mn2+, Ni2+, Fe3+, and Co2+ in aqueous solution at 37°C with 0.154 M NaCl as the supporting electrolyte was studied by pH-metry and mathematical modeling. The formation of complex species of different compositions and stabilities was detected. The stability constants of the complexes were determined. 

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