Complex traits analysis of chicken growth using targeted genetical genomics.

@article{Cabrera2012ComplexTA,
  title={Complex traits analysis of chicken growth using targeted genetical genomics.},
  author={Claudia P Cabrera and Iain Dunn and Mark Fell and Peter J. Wilson and David W. Burt and Dave Waddington and Richard Talbot and Paul M Hocking and Andy Law and Sara Knott and Chris S. Haley and Dirk-Jan de Koning},
  journal={Animal genetics},
  year={2012},
  volume={43 2},
  pages={
          163-71
        }
}
Dissecting the genetic control of complex trait variation remains very challenging, despite many advances in technology. The aim of this study was to use a major growth quantitative trait locus (QTL) in chickens mapped to chromosome 4 as a model for a targeted approach to dissect the QTL. We applied a variant of the genetical genomics approach to investigate genome-wide gene expression differences between two contrasting genotypes of a marked QTL. This targeted approach allows the direct… CONTINUE READING
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