Complex role of tumor cell transforming growth factor (TGF)-βs on breast carcinoma progression

@article{Koli1996ComplexRO,
  title={Complex role of tumor cell transforming growth factor (TGF)-βs on breast carcinoma progression},
  author={Katri M. Koli and Carlos L. Arteaga},
  journal={Journal of Mammary Gland Biology and Neoplasia},
  year={1996},
  volume={1},
  pages={373-380}
}
Growth inhibition by the TGF-βs has been extensively studied in both normal and transformed mammary epithelial cells. It has been proposed that loss of autocrine TGF-β mediated growth regulation is a critical event in breast tumorigenesis and several lines ofin vitro andin vivo data support this hypothesis. However, a positive association between the expression of TGF-βs by tumor cells and the progression or maintenance of breast cancinoma cells has been observed in many studies inin vivo tumor… CONTINUE READING
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Suppressed NK activities and shortened survival associated with high expression of TGF - 13 t in tumor cells of gastric cancer patients

  • S. A. Holden Teicher, G. Ara, G. Chen
  • Proc . Am . Assoc . Cancer Res .
  • 1996

Trans - forming growth factor - 13 type II receptor is infrequently expressed in human breast cancer

  • X-E Wang Yingling
  • Breast J .
  • 1996

Immuno - cytochemical localization of secreted transforming growth factor - 131 to the advancing edges of primary tumors and to lymph node metases of human mammary carcinoma

  • M. E Solomon, A. Castiglioni, V. L. Rothman, G. E Tuszynski
  • Am . J . Pathol .
  • 1995

Mammary tumor suppression by transforming growth factor 131 transgene expression

  • E ten Dijke Jeng, K. K. lwata, V. C. Jordan
  • Proc . Natl . Acad . Sci . U . S . A
  • 1995

Signaling by the transforming growth factor - 13 receptors

  • A. Kasid, K. K. Huff, +4 authors M. E. Lippman
  • Biochim . Bio - phys . Acta
  • 1995

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