Complex regional pain syndrome

@article{Bruehl2015ComplexRP,
  title={Complex regional pain syndrome},
  author={Stephen Bruehl},
  journal={BMJ : British Medical Journal},
  year={2015},
  volume={351}
}
  • S. Bruehl
  • Published 29 July 2015
  • Medicine, Psychology
  • BMJ : British Medical Journal
Complex regional pain syndrome is a chronic pain condition characterized by autonomic and inflammatory features. It occurs acutely in about 7% of patients who have limb fractures, limb surgery, or other injuries. Many cases resolve within the first year, with a smaller subset progressing to the chronic form. This transition is often paralleled by a change from “warm complex regional pain syndrome,” with inflammatory characteristics dominant, to “cold complex regional pain syndrome” in which… 
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The pathophysiology of CRPS is described and the efficiency of new treatments against pain caused by the disease is analyzed to quantitatively analyze the effectiveness of current treatments.
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TLDR
The pathophysiological mechanisms underlying CRPS involve both inflammatory and neurological pathways and vagal nerve stimulation might have the potential for treating CRPS through the cholinergic anti-inflammatory pathway.
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TLDR
A basic overview of the influencing factors, modeling methods, and the characteristics of CRPSIAnimal models is provided to facilitate the choice of appropriate animal models and avoid the interference of the factors influencing animal models on the interpretation of research results.
Pharmacotherapeutic options for complex regional pain syndrome
TLDR
In the opinion, drug therapy should be preferred as early as possible, particularly in warm forms of CRPS to prevent significant functional limitation, psychological distress, and social and economic fallout.
Early adjunct treatment with topical lidocaine results in improved pain and function in a patient with complex regional pain syndrome.
TLDR
A case of topical 5% lidocaine ointment as a non-invasive, inexpensive and effective adjunct treatment in the management of pain in a spinal cord injured patient presenting with early CRPS is presented.
Complex Regional Pain Syndrome Caused by an Axillary Lipoma
TLDR
A rare case of CRPS caused by surgical removal of a left axillary lipoma impinging on the brachial plexus is reported, which highlights the importance of considering CRPS when evaluating differential diagnoses for pre- and post-operative conditions affecting the upper and lower extremities.
Sensory modulation dysfunction is associated with Complex Regional Pain Syndrome
TLDR
The risk index probability clinical tool is provided to be applied by clinicians in order to identify those at risk for CRPS immediately after injury, and screening for SMD is recommended.
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TLDR
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  • S. Bruehl
  • Medicine, Psychology
    Anesthesiology
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TLDR
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TLDR
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