[Complex influence of pharmacological agents on degenerative processes in brain of Drosophila melanogaster mutants].

Abstract

A scheme of complex administration of drugs in the order neuroprotector + neuroactivator + neuroretarder for the treatment of neurodegenerative processes in the brain has been elaborated and tested on a model object representing neurodegenerative mutants of Drosophila melanogaster. The appearance of changes in the brain was delayed when drugs were used separately: donepezil hydrochloride (arisept), 10 - 11 days, epinephrine and nimodipine, 1 - 2 days. The treatment of flies with the same drugs in the order arisept + epinephrine + nimodipine leads to the complete regeneration of D. melanogaster brain tissue to within 15 days of imago life.

Cite this paper

@article{Radysh2006ComplexIO, title={[Complex influence of pharmacological agents on degenerative processes in brain of Drosophila melanogaster mutants].}, author={V. V. Radysh and Dariya V. Maksymiv and Andrey N. Makarenko}, journal={Eksperimental'naia i klinicheskaia farmakologiia}, year={2006}, volume={69 5}, pages={16-9} }