Complex discriminative stimulus properties of (+)lysergic acid diethylamide (LSD) in C57Bl/6J mice

@article{Benneyworth2004ComplexDS,
  title={Complex discriminative stimulus properties of (+)lysergic acid diethylamide (LSD) in C57Bl/6J mice},
  author={M. Benneyworth and R. Smith and R. Barrett and E. sanders-Bush},
  journal={Psychopharmacology},
  year={2004},
  volume={179},
  pages={854-862}
}
RationaleThe drug discrimination procedure is the most frequently used in vivo model of hallucinogen activity. Historically, most drug discrimination studies have been conducted in the rat. With the development of genetically modified mice, a powerful new tool has become available for investigating the mechanisms of drug-induced behavior. The current paper is part of an ongoing effort to determine the utility of the drug discrimination technique for evaluating hallucinogenic drugs in mice… Expand
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