Complex cellular functions of the von Hippel–Lindau tumor suppressor gene: insights from model organisms

  • T Hsu
  • Published 2012 in Oncogene

Abstract

The von Hippel–Lindau tumor suppressor gene (VHL) has attracted intensive interest not only because its mutations predispose carriers to devastating tumors, but also because it is involved in oxygen sensing under physiological conditions. VHL loss-of-function mutations result in organ-specific tumors, such as hemangioblastoma of the central nervous system… (More)
DOI: 10.1038/onc.2011.442

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Cite this paper

@article{Hsu2012ComplexCF, title={Complex cellular functions of the von Hippel–Lindau tumor suppressor gene: insights from model organisms}, author={T Hsu}, journal={Oncogene}, year={2012}, volume={31}, pages={2247-2257} }