Complex Regional Pain Syndrome - Diagnosis, Treatment and Future Perspectives

  title={Complex Regional Pain Syndrome - Diagnosis, Treatment and Future Perspectives},
  author={Sigrid G. L. Fischer and Roberto S.G.M. Perez},
  journal={European neurological review},
Complex regional pain syndrome (CRPS) is a pain syndrome of the extremities that can result in severe disability. CRPS is diagnosed using diagnostic Budapest criteria based on signs and symptoms, whereby sensory, autonomic, vasomotor, motor and trophic disturbances are assessed. Many pathophysiological mechanisms are proposed in the development and disease course of CRPS, starting with exaggerated inflammation and resulting in vascular deregulation, central sensitisation and cortical… 

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