Completion of the nucleotide sequence of the Enterococcus faecalis conjugative virulence plasmid pAD1 and identification of a second transfer origin.

@article{Francia2001CompletionOT,
  title={Completion of the nucleotide sequence of the Enterococcus faecalis conjugative virulence plasmid pAD1 and identification of a second transfer origin.},
  author={Mar{\'i}a Victoria Francia and Wolfgang Haas and Reinhard Wirth and E Samberger and AB Muscholl-Silberhorn and Michael S. Gilmore and Yasuyoshi Ike and Keith E. Weaver and Florence Y-P An and Don B. Clewell},
  journal={Plasmid},
  year={2001},
  volume={46 2},
  pages={117-27}
}
pAD1 is a 59.3-kb plasmid in Enterococcus faecalis that has been the subject of intense investigation with regard to its pheromone-inducible conjugation behavior as well as its contribution to virulence. Approximately two-thirds of the pAD1 nucleotide sequence has been previously reported. Here we report on an analysis of the final approximately 22 kb, a significant portion of which is believed to encode structural genes associated with conjugation. The conjugation-related region was also found… CONTINUE READING