Complete replacement of basic amino acid residues with cysteines in Rickettsia prowazekii ATP/ADP translocase.

Abstract

The ATP/ADP translocase (Tlc) of Rickettsia prowazekii is a basic protein with isoelectric point (pI)=9.84. It is conceivable, therefore, that basic residues in this protein are involved in electrostatic interactions with negatively charged substrates. We tested this hypothesis by individually mutating all basic residues in Tlc to Cys. Unexpectedly… (More)

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Cite this paper

@article{Alexeyev2002CompleteRO, title={Complete replacement of basic amino acid residues with cysteines in Rickettsia prowazekii ATP/ADP translocase.}, author={Mikhail F. Alexeyev and Herbert H. Winkler}, journal={Biochimica et biophysica acta}, year={2002}, volume={1565 1}, pages={136} }