Complete primary structure of prostatropin, a prostate epithelial cell growth factor.

  title={Complete primary structure of prostatropin, a prostate epithelial cell growth factor.},
  author={John W. Crabb and Lyman G Armes and Steve A Carr and Christopher Mark Johnson and Glenn D Roberts and Robert S. Bordoli and Wallace L. Mckeehan},
  volume={25 18},
Bovine brain prostatropin is a potent and essential mitogen for prostate epithelial cell growth. The major form of prostatropin contains 154 amino acid residues in a single amino terminally blocked chain corresponding to a molecular weight of 17,400. The amino acid sequence of the 150 carboxy-terminal residues of prostatropin was derived by Edman degradation of overlapping peptides primarily generated by cleavage at lysyl and glutamyl residues. Analysis of the amino-terminal tetradecapeptide by… CONTINUE READING


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