Complete nucleotide sequence of a circular plasmid from the Lyme disease spirochete, Borrelia burgdorferi.

@article{Dunn1994CompleteNS,
  title={Complete nucleotide sequence of a circular plasmid from the Lyme disease spirochete, Borrelia burgdorferi.},
  author={John J. Dunn and S R Buchstein and Louise Butler and S Fisenne and Didier Polin and B N Lade and Benjamin J. Luft},
  journal={Journal of bacteriology},
  year={1994},
  volume={176 9},
  pages={2706-17}
}
We have determined the complete nucleotide sequence of a small circular plasmid from the spirochete Borrelia burgdorferi Ip21, the agent of Lyme disease. The plasmid (cp8.3/Ip21) is 8,303 bp long, has a 76.6% A+T content, and is unstable upon passage of cells in vitro. An analysis of the sequence revealed the presence of two nearly perfect copies of a 184-bp inverted repeat sequence separated by 2,675 bp containing three closely spaced, but nonoverlapping, open reading frames (ORFs). Each… CONTINUE READING
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