Complete immunosuppressive withdrawal as a uniform approach to post-transplant lymphoproliferative disease in pediatric liver transplantation.

@article{Hurwitz2004CompleteIW,
  title={Complete immunosuppressive withdrawal as a uniform approach to post-transplant lymphoproliferative disease in pediatric liver transplantation.},
  author={Melissa Hurwitz and Dev M. Desai and Kenneth L. Cox and William Berquist and Carlos O. Esquivel and Maria T Millan},
  journal={Pediatric transplantation},
  year={2004},
  volume={8 3},
  pages={267-72}
}
Epstein-Barr virus (EBV)-associated post-transplant lymphoproliferative disease (PTLD) in pediatric liver transplant recipients is associated with a high mortality (up to 60%) and the younger age groups, who are predominantly EBV-naïve, are at highest risk for development of this disease. The aim of this study is to assess, in this high-risk group, patient outcome and graft loss to rejection when complete withdrawal of immunosuppressive agents (IMS) is instituted as the mainstay of treatment in… CONTINUE READING

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