Complete genomic sequence and phylogenetic analysis of the lactate dehydrogenase-elevating virus (LDV).

@article{Godeny1993CompleteGS,
  title={Complete genomic sequence and phylogenetic analysis of the lactate dehydrogenase-elevating virus (LDV).},
  author={Elmer K. Godeny and Li-fang Chen and Suresh N. Kumar and S L Methven and Eugene V. Koonin and Margo A Brinton},
  journal={Virology},
  year={1993},
  volume={194 2},
  pages={585-96}
}
The apparently complete sequence of the RNA genome of the neurovirulent isolate of lactate dehydrogenase-elevating virus (LDV-C) has been determined. The LDV-C genome is at least 14,222 nucleotides in length and contains eight open reading frames (ORFs). ORF 1a, which encodes a protein of 242.8 kDa and is located at the 5' end of the genome, contains at least two putative papain-like cysteine protease domains, and one putative chymotrypsin-like serine protease domain. This ORF terminates with a… CONTINUE READING