Complete genomic analysis of a Bangladeshi G1P[8] rotavirus strain detected in 2003 reveals a close evolutionary relationship with contemporary human Wa-like strains.

@article{Rahman2010CompleteGA,
  title={Complete genomic analysis of a Bangladeshi G1P[8] rotavirus strain detected in 2003 reveals a close evolutionary relationship with contemporary human Wa-like strains.},
  author={Mustafizur Rahman and Jelle Matthijnssens and Farjana Saiada and Zahid Hassan and Elisabeth Heylen and Tasnim Azim and Marc van Ranst},
  journal={Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases},
  year={2010},
  volume={10 6},
  pages={
          746-54
        }
}
More than 120 variants of rotavirus strains with different VP7 (G type) and VP4 (P type) combinations are reported thus far. Among them Wa-like G1P[8] rotaviruses are the most common human strains worldwide. However, characterization of their entire genome complement is limited to a few old prototype strains, and no complete genome data for any G1P[8] strain isolated in the last decade are available. Both the currently licensed rotavirus vaccines Rotarix and RotaTeq possess the G1 and P[8… CONTINUE READING

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