Complete genome sequences of Mycobacterium tuberculosis strains CCDC5079 and CCDC5080, which belong to the Beijing family.

@article{Zhang2011CompleteGS,
  title={Complete genome sequences of Mycobacterium tuberculosis strains CCDC5079 and CCDC5080, which belong to the Beijing family.},
  author={Yuanyuan Zhang and Chen Chen and Jie Liu and Haijun Deng and Aizhen Pan and Lishui Zhang and Xiuqin Zhao and Mingxiang Huang and Bing Lu and Haiyan Dong and Pengcheng Du and Weijun Chen and Kanglin Wan},
  journal={Journal of bacteriology},
  year={2011},
  volume={193 19},
  pages={5591-2}
}
Mycobacterium tuberculosis is one of most prevalent pathogens in the world. Drug-resistant strains of this pathogen caused by the excessive use of antibiotics have long posed serious threats to public health worldwide. A broader picture of drug resistance mechanisms at the genomic level can be obtained only with large-scale comparative genomic methodology. Two closely related Beijing family isolates, one resistant to four first-line drugs (CCDC5180) and one sensitive to them (CCDC5079), were… CONTINUE READING
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