Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2)

  title={Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2)},
  author={Stephen D. Bentley and Keith F. Chater and A.-M. Cerde{\~n}o-T{\'a}rraga and Gregory L Challis and Nicholas R Thomson and Keith D. James and David Eisenbud Joe Harris and Michael A. Quail and Helen M. Kieser and David K Harper and Alex Bateman and Susan Brown and Govind Chandra and Carton W. Chen and Matthew Collins and Ann Cronin and A. S. Fraser and Arlette Goble and J. Hidalgo and Tom Hornsby and Shauna Howarth and C.-H. Huang and T. Kieser and L. Larke and Lee Murphy and Karen Oliver and Susan O'neil and Ester Rabbinowitsch and M.-A. Rajandream and Kim Rutherford and Simon Rutter and Katharine T Seeger and David Saunders and Stephen Sharp and Robert Squares and Steven Squares and Kent E Taylor and Timothy H Warren and Andreas Wietzorrek and John P. L. Woodward and Bart G. Barrell and Julian Parkhill and David A. Hopwood},
Streptomyces coelicolor is a representative of the group of soil-dwelling, filamentous bacteria responsible for producing most natural antibiotics used in human and veterinary medicine. Here we report the 8,667,507 base pair linear chromosome of this organism, containing the largest number of genes so far discovered in a bacterium. The 7,825 predicted genes include more than 20 clusters coding for known or predicted secondary metabolites. The genome contains an unprecedented proportion of… CONTINUE READING
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Genome sequence of an industrial microorganism Streptomyces avermitilis : deducing the ability of producing secondary metabolites

  • S. Ōmura
  • Proc . Natl Acad . Sci . USA
  • 2001

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