Complete genome sequence of an overattenuated highly pathogenic porcine reproductive and respiratory syndrome virus.

@article{Wu2012CompleteGS,
  title={Complete genome sequence of an overattenuated highly pathogenic porcine reproductive and respiratory syndrome virus.},
  author={Jiajun Wu and Nanhua Chen and Wei Han and Zhen Cao and Xiaoyu Deng and Lilin Wang and Xiuling Yu and Zhi Zhou and Xiangdong Li and Jishu Shi and Kegong Tian},
  journal={Journal of virology},
  year={2012},
  volume={86 11},
  pages={6381-2}
}
JXA1-P170 is an overattenuated highly pathogenic porcine reproductive and respiratory syndrome virus (HP-PRRSV) that has been passaged in vitro 170 times. Vaccination with JXA1-P170 cannot protect pigs against JXA1 challenge. Compared with the parental virus JXA1, JXA1-P170 contains 1 nucleotide (nt) deletion and 113 nt mutations leading to 59 amino acid substitutions. Here we announce the first complete genome sequence of the overattenuated HP-PRRSV. 
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