Complete enumeration of elementary flux modes through scalable demand-based subnetwork definition

@article{Hunt2014CompleteEO,
  title={Complete enumeration of elementary flux modes through scalable demand-based subnetwork definition},
  author={Kristopher A. Hunt and James P. Folsom and Reed L. Taffs and Ross P. Carlson},
  journal={Bioinformatics},
  year={2014},
  volume={30 11},
  pages={1569-78}
}
MOTIVATION Elementary flux mode analysis (EFMA) decomposes complex metabolic network models into tractable biochemical pathways, which have been used for rational design and analysis of metabolic and regulatory networks. However, application of EFMA has often been limited to targeted or simplified metabolic network representations due to computational demands of the method. RESULTS Division of biological networks into subnetworks enables the complete enumeration of elementary flux modes (EFMs… CONTINUE READING
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Parallel computation of elementary flux modes in metabolic networks using global arrays

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