Complete covalent structure of a human immunoglobulin D: sequence of the lambda light chain.

@article{Takahashi1983CompleteCS,
  title={Complete covalent structure of a human immunoglobulin D: sequence of the lambda light chain.},
  author={Yasuhiro Takahashi and Nobuhiro Takahashi and Daniel T{\'e}taert and Frank W. Putnam},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1983},
  volume={80 12},
  pages={3686-90}
}
We have determined the amino acid sequence of the lambda light chain of human IgD WAH. Together with the sequence of the delta heavy chain already reported, this establishes the complete covalent structure of a human immunoglobulin D. The sequence determination was greatly aided by our ability to use high-pressure liquid chromatography to purify large peptides, including one large fragment extending from Ser-81 through the carboxyl terminus. The IgD molecule is a four-chain monomer of Mr… CONTINUE READING