Complete cDNA sequence and tissue localization of N-RAP, a novel nebulin-related protein of striated muscle.

@article{Luo1997CompleteCS,
  title={Complete cDNA sequence and tissue localization of N-RAP, a novel nebulin-related protein of striated muscle.},
  author={G Luo and J Q Zhang and T P Nguyen and Amy H. Herrera and Bruce C. Paterson and Robert Horowits},
  journal={Cell motility and the cytoskeleton},
  year={1997},
  volume={38 1},
  pages={
          75-90
        }
}
We have cloned and sequenced the full-length cDNA of N-RAP, a novel nebulin-related protein, from mouse skeletal muscle. The N-RAP message is specifically expressed in skeletal and cardiac muscle, but is not detected by Northern blot in non-muscle tissues. The full-length N-RAP cDNA contains an open reading frame of 3,525 base pairs which is predicted to encode a protein of 133 kDa. A 587 amino acid region near the C-terminus is 45% identical to the actin binding region of human nebulin… CONTINUE READING

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