Complete and Incomplete Genome Packaging of Influenza A and B Viruses

@inproceedings{Nakatsu2016CompleteAI,
  title={Complete and Incomplete Genome Packaging of Influenza A and B Viruses},
  author={Sumiho Nakatsu and Hiroshi Sagara and Yuko Sakai-Tagawa and Norio Sugaya and Takeshi Noda and Yoshihiro Kawaoka},
  booktitle={mBio},
  year={2016}
}
UNLABELLED The genomes of influenza A and B viruses comprise eight segmented, single-stranded, negative-sense viral RNAs (vRNAs). Although segmentation of the virus genome complicates the packaging of infectious progeny into virions, it provides an evolutionary benefit in that it allows viruses to exchange vRNAs with other strains. Influenza A viruses are believed to package their eight different vRNAs in a specific manner. However, several studies have shown that many viruses are noninfectious… CONTINUE READING
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