Complete Nucleotide Sequence of Human Vasoactive Intestinal Peptide/PHM‐27 Gene and Its Inducible Promoter a

@article{Yamagami1988CompleteNS,
  title={Complete Nucleotide Sequence of Human Vasoactive Intestinal Peptide/PHM‐27 Gene and Its Inducible Promoter a},
  author={T. Yamagami and K. Ohsawa and M. Nishizawa and C. Inoue and E. Gotoh and N. Yanaihara and H. Yamamoto and H. Okamoto},
  journal={Annals of the New York Academy of Sciences},
  year={1988},
  volume={527}
}
  • T. Yamagami, K. Ohsawa, +5 authors H. Okamoto
  • Published 1988
  • Biology, Medicine
  • Annals of the New York Academy of Sciences
  • We have previously shown that the VIP precursor contains a novel PHI-27-like peptide, PHM-27, and that the synthesis of the prepro-VIP/PHM-27 mRNA is induced with cAMP and TPA in human neuroblastoma cells. In this study, we have determined the complete nucleotide sequence of the human VIP/PHM-27 gene. The gene spans 8,837 bp and consists of seven exons and six introns. Exon I of 165 bp consists of the 5' untranslated region of the gene, exon II of 117 bp encodes the signal peptide of prepro-VIP… CONTINUE READING
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